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AGEA for the Developing Mouse Brain is used to understand how voxels of the brain are related by gene expression (Correlation), and to find genes expressed at a particular voxel (Gene Finder). Click on the AGEA tab to get started.

CORRELATION MODE

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In correlation mode, use the seed selector to select a starting age by clicking on your age of interest. The next three columns will show you the age you selected flanked by the nearest developmental ages. Also shown in the column headers are the structure and location of the selected voxel and the Pearson's correlations (please see Informatics whitepaper available from the Documentation tab).

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Select a "seed" voxel using the cross hairs in the left hand column from one of the planes of view. The three columns to the right show correlation maps of how other voxels are related to the seed voxel based upon the gene expression of approximately 2000 genes.

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Once a seed is selected and correlation maps are shown, you can retrieve a list of genes enriched in the region correlated to the seed voxel.

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First, click on the "Gene Finder" tab. Then, click on "Find Genes" for the particular age you are interested in.

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