1 Leaky Integrate and Fire (LIF)
Standard circuit representation of a resistor and capacitor in parallel with a leaky membrane.
2 LIF + Reset Rules (LIF-R)
LIF with biologically-derived threshold and voltage reset rules in addition to a biologically derived threshold decay.
3 LIF + Afterspike Currents (LIF-ASC)
LIF with spike-induced currents to model long-term effects of voltage-activated ion channels.
4 LIF-R + Afterspike Currents (LIF-R-ASC)
LIF with additional Reset Rules and Afterspike Currents.
5 LIF-R-ASC + Threshold Adaptation (LIF-R-ASC-A)
All of the above, with an additional voltage-dependent component of threshold.
Models with active conductances at the soma and passive dendritic morphology based on full 3D reconstruction.
|Biophysical, all-active||Models with active conductances at the soma and along the dendritic morphology based on full 3D reconstruction.|
See the perisomatic biophysical and GLIF technical whitepapers for more details on how these models were created.
A cell's electrophysiology page displays all available models. Choose a model to see its simulated response to all stimuli presented to the cell. If the required sweeps are available, two model evaluation metrics are computed per model: