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ATLAS DRAWINGS AND ONTOLOGIES

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A set of high resolution digital reference atlases have been created to provide neuroanatomical context to in situ hybridization, microarray, RNA-sequencing and axonal projection data.

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The following Atlases are available through the API (click on Atlas ID to launch the interactive atlas viewer):

Atlas ID

 

Atlas Name

Image Type

Ontology

StructureGraph ID

GraphicGroupLabels

1

Image Modified

"Mouse, P56,  Coronal"

"Atlas - Adult Mouse"

"Mouse Brain Atlas"

1

[28,159226751]

2

Image Modified

"Mouse, P56, Sagittal"

"Atlas - Adult Mouse"

"Mouse Brain Atlas"

1

[28,159226751]

181276165

Image Modified

"Developing Mouse, P56"

"Atlas - Developing Mouse"

"Developing Mouse Brain Atlas"

17

[32,167675952]

181276164

Image Modified

"Developing Mouse, P14"

"Atlas - Developing Mouse"

"Developing Mouse Brain Atlas"

17

[32]

181276162

Image Modified

"Developing Mouse, P4"

"Atlas - Developing Mouse"

"Developing Mouse Brain Atlas"

17

[32]

181276160

Image Modified

"Developing Mouse, E18.5"

"Atlas - Developing Mouse"

"Developing Mouse Brain Atlas"

17

[32]

181276151

Image Modified

"Developing Mouse, E15.5"

"Atlas - Developing Mouse"

"Developing Mouse Brain Atlas"

17

[32]

181276130

Image Modified

"Developing Mouse, E13.5"

"Atlas - Developing Mouse"

"Developing Mouse Brain Atlas"

17

[32]

181275741

Image Modified

"Developing Mouse, E11.5"

"Atlas - Developing Mouse"

"Developing Mouse Brain Atlas"

17

[32,126768961]

138322605

Image Modified

"Human, 34 years, Cortex - Gyral"

"Atlas - Developing Human"

"Developing Human Brain Atlas"

16

[31,113753815,113753816,141667008]

265297126

Image Modified

"Human, 34 years, Cortex - Mod. Brodmann"

"Atlas - Developing Human Brodmann"

"Developing Human Brain Atlas"

16

[31,113753816,141667008,265297118]

3

Image Modified

"Human, 21 pcw"

"Atlas - Developing Human"

"Developing Human Brain Atlas"

16

[31,113753816,141667008]

287730656

Image Modified

"Human, 21 pcw - Brainstem"

"Atlas - Developing Human"

"Developing Human Brain Atlas"

16

[31,141667008]

138322603

Image Modified

"Human, 15 pcw"

"Atlas - Developing Human"

"Developing Human Brain Atlas"

16

[31,141667008]

265297125

Image Modified

"Human Brain Atlas Guide "

"Atlas - Human"

"Human Brain Atlas"

10

[265297119,266932194,266932196,266932197]

Downloading Atlas Images And Graphics

The sections for each Atlas come from a single AtlasDataSet (child class of SectionDataSet) and single Specimen. Typically, only a subset of AtlasImages (child class of SectionImage) is used for the reference atlas. An "annotated" image is identified by the SubImage "annotated" attribute and the corresponding image type. Please note that multiple line example RMA queries on this page use the "+" character to represent spaces for browser compatibility.

Examples:

  • "Atlas - Adult Mouse" images for the "Mouse, P56  Coronal" atlas

    No Format
    
    http://api.brain-map.org/api/v2/data/query.xml?criteria=model::AtlasImage,
    rma::criteria,
    [annotated$eqtrue],
    atlas_data_set(atlases[id$eq1]),
    alternate_images[image_type$eq'Atlas+-+Adult+Mouse'],
    rma::options[order$eq'sub_images.section_number'][num_rows$eqall]
    
  • "Atlas - Developing Human" images for the "Human, 34 years, Cortex - Gyral" atlas

    No Format
    
    http://api.brain-map.org/api/v2/data/query.xml?criteria=model::AtlasImage,
    rma::criteria,
    [annotated$eqtrue],
    atlas_data_set(atlases[id$eq138322605]),
    alternate_images[image_type$eq'Atlas+-+Developing+Human'],
    rma::options[order$eq'sub_images.section_number'][num_rows$eqall]
    

Once the annotated images have been identified, the image ID can be used to download the colorized and labeled images using the Image Download Service and the vector graphics using the SVG Download Service.

Examples:

  • Download colorized and labeled image for one "Mouse, P56  Coronal" atlas image

    No Format
    
    http://api.brain-map.org/api/v2/atlas_image_download/100960248?downsample=4&annotation=true
    
  • View the vector graphics for one "Human, 34 years, Cortex - Gyral" atlas image

    No Format
    
    http://api.brain-map.org/api/v2/svg/112360908?groups=31,113753815,113753816,141667008&downsample=8
    
  • Download the vector graphics for one "Human, 34 years, Cortex - Gyral" atlas image

    No Format
    
    http://api.brain-map.org/api/v2/svg_download/112360908?groups=31,113753815,113753816,141667008&downsample=8
    

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Major structural ontologies used in the Allen Brain Atlas Data Portal:

Ontology ID

Ontology Name

StructureGraph
ID

Uses

1

"Mouse Brain Atlas"

1

Mouse Brain, Mouse Connectivity

  • Reference Atlases
  • Brain Explorer, AGEA
  • Informatics quantification of ISH data
  • Informatics quantification of projection data
  • Search services

12

"Developing Mouse Brain Atlas"

17

Developing Mouse Brain

  • Reference Atlases
  • Brain Explorer, AGEA
  • Informatics quantification of ISH data
  • Search services

7

"Human Brain Atlas"

10

Human Brain

  • Annotation of microarray Sampling Sites
  • Brain Explorer
  • Heatmap and search services
  • "Hot spot" annotation of ISH data
  • Human Brain Atlas Guide

11

"Developing Human Brain Atlas"

16

Developing Human Brain

  • Reference Atlases
  • Annotation of RNA-sequencing and microarray Sampling Sites
  • Heatmap and search services
  • "Hot spot" annotation of ISH data

4

"Non-Human Primate Brain Atlas"

8

Non-Human Primate

  • Annotation of microarray Sampling Sites
  • Heatmap and search services
  • "Hot spot" annotation of ISH data

10

"Glioblastoma"

15

Glioblastoma, Human Glioblastoma RNASeq

  • Annotation of tumor features on H&E and ISH data
  • Annotation of RNA-Seq sampling sites

From the API, Structure and Ontology information can be downloaded in various formats.

Examples:

  • Download the "Human Brain Atlas" ontology as a CSV file

    No Format
    
    http://api.brain-map.org/api/v2/data/query.csv?criteria=model::Structure,
    rma::criteria,[ontology_id$eq7],
    rma::options[order$eq%27structures.graph_order%27][num_rows$eqall]
    
  • Download the "Mouse Brain Atlas" ontology as a hierarchically structured json file

    No Format
    
    http://api.brain-map.org/api/v2/structure_graph_download/1.json
    
  • Download the "Developing Human Brain Atlas" ontology as a hierarchically structured json file

    No Format
    
    http://api.brain-map.org/api/v2/structure_graph_download/16.json