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Column

Definition

Tumor

Specimen ID of the tumor, linking to the #Specimen Specimen Detail Page

Molecular Subtype

Classical: chromosome 7 amplification (EGFR), paired with chromosome 10 loss. Mesenchymal: noted for focal hemizygous deletions of a region at 17q11.2 (NF1). Proneural: defined by alterations of PDGFRA and point mutations in IDH1. Neural: typified by the expression of neuronal markers such as NEFL, GABRA1, SYT1, and SLC12A5.

Extent of Resection

Degree to which tumor tissue was surgically removed

Surgery

Whether the tumor was a primary surgery, or removal of a subsequent recurrent tumor

MGMT Methylation

A diagnostic test result referring to whether a tumor’s O-6-methylguanine-DNA methyltransferase DNA repair gene was methylated

Survival Days

Number of days from the initial diagnosis

EGFR Amplification

A diagnostic test result referring to whether a particular tumor’s epidermal growth factor receptor (EGFR) gene had multiple copies

Initial KPS

Karnofsky Performance Status is a measure of functional impairment (on a scale of 0-100, 0 referring to dead, 50 to requiring considerable assistance and frequent medical care, and 100 referring to no evidence of disease)

Age

Age in years at the time of diagnosis

SNI Link

Link to the Swedish Neurological Institute page for this donor (Registration required)

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Column

Description

Specimen

Clicking on this link will take you to a #Specimen Specimen Detail Page

Study

Indicates which study the samples were assayed

Donor

Donor age and gender

Location

Location in the brain from which the tumor was removed

Molecular Subtype

Classical: chromosome 7 amplification (EGFR), paired with chromosome 10 loss. Mesenchymal: noted for focal hemizygous deletions of a region at 17q11.2 (NF1). Proneural: defined by alterations of PDGFRA and point mutations in IDH1. Neural: typified by the expression of neuronal markers such as NEFL, GABRA1, SYT1, and SLC12A5.

Normalized Area

The fraction of the selected “structure” in the specimen sub-block

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Column Header

Description

Entrez ID

Unique identifier from the National Center for Biotechnology Information (NCBI) database for gene-specific information

Gene Symbol

The gene symbol, which is a short abbreviated form of the gene name. Clicking on

Lightbox
ImageNameMETExps.jpg

this link

will take you to all GBM experiments performed on this gene

Specimen

Clicking on this link will take you to a #Specimen Specimen Detail Page

Donor

Donor age and gender

Molecular Subtype

Classical: chromosome 7 amplification (EGFR), paired with chromosome 10 loss. Mesenchymal: noted for focal hemizygous deletions of a region at 17q11.2 (NF1). Proneural: defined by alterations of PDGFRA and point mutations in IDH1. Neural: typified by the expression of neuronal markers such as NEFL, GABRA1, SYT1, and SLC12A5.

Target Sum

Sum of gene expression energy over all the target structures

Fold Change

The measure describing how gene expression changes when comparing the target structure(s) expression energy to the contrast structure(s) expression energy

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Column

Description

Entrez ID

Unique identifier from the National Center for Biotechnology Information (NCBI) database for gene-specific information

Gene Symbol

The official gene symbol, which is a short abbreviated form of the gene name. Clicking on

Lightbox
ImageNameMETExps.jpg

this link

will take you to all GBM experiments performed on this gene

Specimen

Clicking on this link will take you to a #Specimen Specimen Detail Page

Donor

Donor age and gender

Molecular Subtype

Classical: chromosome 7 amplification (EGFR), paired with chromosome 10 loss. Mesenchymal: noted for focal hemizygous deletions of a region at 17q11.2 (NF1). Proneural: defined by alterations of PDGFRA and point mutations in IDH1. Neural: typified by the expression of neuronal markers such as NEFL, GABRA1, SYT1, and SLC12A5.

Average Expression

The sum of expressing pixels divided by sum product of pixels of that tumor feature

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This panel displays information on patient and tumor, and on how the tumor was subdivided into blocks. This panel is arrived at by toggling the "View Patient, Tumor and MRI Summary" button in the Tumor Subdivision section of the #Specimen Specimen Detail Page.

Description of Donor ID

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