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Model Name

Description

1 Leaky Integrate and Fire (LIF)

Standard circuit representation of a resistor and capacitor in parallel with a leaky membrane.

2 LIF + Reset Rules (LIF-R)

LIF with biologically-derived threshold and voltage reset rules in addition to a biologically derived threshold decay.

3 LIF + Afterspike Currents (LIF-ASC)

LIF with spike-induced currents to model long-term effects of voltage-activated ion channels.

4 LIF-R + Afterspike Currents (LIF-R-ASC)

LIF with additional Reset Rules and Afterspike Currents.

5 LIF-R-ASC + Threshold Adaptation (LIF-R-ASC-A)

All of the above, with an additional voltage-dependent component of threshold.

Biophysical, perisomatic

Models with active conductances at the soma and passive dendritic morphology based on full 3D reconstruction.

Biophysical, all-activeModels with active conductances at the soma and along the dendritic morphology based on full 3D reconstruction.

See the perisomatic biophysical and GLIF technical whitepapers for more details on how these models were created.

A cell's electrophysiology page displays all available models.  Choose a model to see its simulated response to all stimuli presented to the cell.  If the required sweeps are available, two model evaluation metrics are computed per model:

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