Cell Types Data

Searching the Database

With the initial launch of the Allen Cell Types Database, we include electrophysiological recordings from 248 individual cells,

Filters

Cell Feature Filters

Stimulus Types

ELECTROPHYSIOLOGY STIMULI STRATEGY AND DETAILS

Different sets of stimulation waveforms were used in order to:

  1. Interrogate intrinsic membrane mechanisms that underlie the input/output function of neurons
    1. Linear and non-linear subthreshold properties
    2. Action potential initiation and propagation
    3. Afterhyperpolarization/afterdepolarization
  2. Understand aspects of neural response properties in vivo
    1. Stimulation frequency dependence (theta vs. gamma) of spike initiation mechanisms
    2. Ion channel states due to different resting potentials in vivo
  3. Construct and test computational models of varying complexity emulating the neural response to stereotyped stimuli
    1. Generalized leaky-integrate-and-fire (GLIF) models
    2. Biophysically and morphologically realistic conductance-based compartmental models


1a

1b

1c

2a

2b

3a

3b

Ramp

X

X

 

 

 

X

X

Long Square

X

X

 

 

 

 

X

Short Square

 

X

X

 

 

X

 

Short Square - Hold

 

X

 

 

X

 

 

Short Square - Triple








Noise (1 & 2)

 

 

 

X

 

X

 

Ramp to Rheobase




X


X


Square Suprathreshold



X




X

Square Subthreshold

X






X

Neuronal Models