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- Download structure projection signal statistics for one VISp injection experiment exclusive of injection area
- Download injection site statistics for the same experiment
- See the experiment detail page for the same experiment in the web application
- Take a look at the Cortico-thalamic Projection example application
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- The Source Search function retrieves experiments by anatomical location of the injection site.
- The Target Search function returns a rank list of experiments by signal volume in the user specified target structure(s).
- The Spatial Search function returns a rank list of experiments by density of signal in the user specified target voxel location.
- The Injection Coordinate Search function returns a rank list of experiments by distance of their injection site to a user - specified reference space coordinateseed location.
- The Correlation Search function enables the user to find experiments that have a similar spatial projection profile to a seed experiment when compared over a user-specified domain.
The projection grid search service is available through both the Web application and API.
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To perform a Source Search, a user specifies a set of source structures. The service returns all experiments for which either the primary injection structure or one of its secondary injection structures corresponding to one of the specified source structures or their descendents in the ontology. The search results can also be filtered by a specified list of transgenic lines.
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- Source search for experiments with injection in the isocortex
Code Block http://api.brain-map.org/api/v2/data/query.xml?criteria= service::mouse_connectivity_injection_structure[injection_domain$eqIsocortex]
- Source search for experiments performed on wild-type specimens and with injection in the isocortex
Code Block http://api.brain-map.org/api/v2/data/query.xml?criteria= service::mouse_connectivity_injection_structure[injection_domain$eqIsocortex][transgenic_lines$eq0]
- Source search for experiments performed on Syt6-Cre_KI148 cre-line specimens and with injection in the isocortex
Code Block http://api.brain-map.org/api/v2/data/query.xml?criteria= service::mouse_connectivity_injection_structure[injection_domain$eqIsocortex][transgenic_lines$eq'Syt6-Cre_KI148']
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Figure: Screenshot of source search results in the web application for experiments with injection in the isocortex. The injection location of each experiment is shown as a sphere on the 3D injection map.
Target Search
To perform a a Target Search, the user specifies a set of target structures. The service returns a rank list of experiments by signal volume in the target structures which are above a minimum threshold. The target structure specification can be further refined by hemisphere. The search results can also be filtered by a list of source structures and/or list of transgenic lines.
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Figure: Screenshot of top returns of a correlation search for experiments with similar projection to a MOp injection experiment (top-left) within the thalamus