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  • Find Structure ID for "thalamus" (id = 4392)
    Code Block
    http://api.brain-map.org/api/v2/data/query.xml?criteria=model::Structure,
    rma::criteria,[name$il'thalamus'],ontology[name$eq'Human Brain Atlas'],
    rma::options[only$eq'structures.id']
    
  • Find Structure ID for "cerebral cortex" (id = 4008)
    Code Block
    http://api.brain-map.org/api/v2/data/query.xml?criteria=model::Structure,
    rma::criteria,[name$il'cerebral cortex'],ontology[name$eq'Human Brain Atlas'],
    rma::options[only$eq'structures.id']
    
  • Use Structure IDs as parameters to the connected service
    Code Block
    http://api.brain-map.org/api/v2/data/query.xml?criteria=
        service::human_microarray_differential[structures1$eq4008][structures2$eq4392]
    
  • Visualize the same search result in the Web application Image Removed 

Image Added

Figure: Screenshot of top returns of a differential search for genes with higher expression in the thalamus than the cerebral cortex. Z-score heatmap shows enrichment (red) in the thalamus (structure color: light green) compare to other brain regions.

Usage of this service is demonstrated in the SPM example application.

Correlative search

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