Versions Compared

Key

  • This line was added.
  • This line was removed.
  • Formatting was changed.

...

Color Key

Study

Description

Anatomic Structures ISH Survey

Initial Primary screen of 8 tumors with probes to 344 glioblastoma-enriched genes for 343 genes enriched in glioblastoma

Anatomic Structures RNA-Seq

Screen of 5 structures (Leading Edge, Infiltrating Tumor, Cellular Tumor, Microvascular Proliferation, and Pseudopalisading Cells Around Necrosis) identified by H&E staining in . A total of 122 RNA samples were generated from 10 tumors.

Anatomic Structures ISH for Enriched Genes

Final Subsequent screen of 29 tumors with 38 probes to for 37 genes enriched in particular anatomic glioblastoma structures as identified in Anatomic Structures RNA-Seq study Study

Cancer Stem Cells ISH Survey

Initial Primary screen of 16 tumors with 61 probes to 56 probes for 55 genes enriched in putative cancer stem cell-enriched genes to identify cells, resulting in a 20 probe reference set, which was then used in an extensive screen of 41 42 tumors

Cancer Stem Cells RNA-Seq

Screen of 35 types clusters of putative cancer stem cell clusters cells identified by ISH with a 17 reference probe reference set in subset (validated in the Cancer Stem Cells ISH Survey). A total of 148 RNA samples were generated from 34 tumors

Cancer Stem Cells ISH for Enriched Genes

Final Subsequent screen of 37 tumors with 77 probes to for 76 genes enriched in clusters of putative cancer stem cell clusters as cells identified in the Cancer Stem Cells RNA-Seq study Study

KEY FEATURES:

In Situ Hybridization (ISH): Cellular resolution gene expression image data with adjacent hematoxylin and eosin (H&E)-stained sections that have been manually annotated for anatomic structures.

...