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Feature | Description |
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Upstroke:downstroke ratio | The average ratio between the absolute values of the action potential peak upstroke (i.e. max dV/dt) and the action potential peak downstroke (i.e. min dV/dt) for "Short Square" pulses. |
Fast AP trough | Minimum value of the membrane potential in the interval lasting 5 ms after the peak of the first action potential for the minimum amplitude "Long Square eliciting " stimulus that elicited an action potential. |
FI curve slope | Frequency response Slope of the frequency response (in spikes/sec) vs. stimulus intensity slope (in pA) curve based on a linear regression for all suprathreshold "Long Square" sweeps. |
Rheobase | Minimum stimulus amplitude eliciting an action potential from "Long Square" sweeps. |
Ramp AP Time | Average time of the peak response of the first action potential for "Ramp" sweeps. |
Resting Vm | Average resting potential of across all "Long Square" sweeps. |
Please read the electrophysiology technical white paper (TODO) for a complete list of computed features and their interpretations.
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Model Name | Description |
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Biophysical, perisomatic | Models with active conductances at the soma and morphology based on full 3D reconstruction. |
1 Leak Leaky Integrate and Fire (LIF) | Membrane potential evolves as a function of neuron properties (capacitance, membrane conductance, resting potential) and external current combined with a reset rule if membrane potential surpasses a fixed voltage threshold. |
2 LIF + Reset Rules (LIF-R) |
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3 LIF + Afterspike Currents (LIF-ASC) |
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4 LIF-R + Afterspike Currents (LIF-R-ASC) |
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5 LIF-R-ASC + Threshold Adaptation (LIF-R-ASC-A) |
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