Models with active conductances at the soma and morphology based on full 3D reconstruction.
1 Leaky Integrate and Fire (LIF)
Membrane potential evolves as a function of neuron properties and external current and is reset to a fixed value if it surpasses a fixed threshold.
2 LIF + Reset Rules (LIF-R)
LIF with biologically-defined afterspike threshold decay rules.
3 LIF + Afterspike Currents (LIF-ASC)
LIF with spike-induced currents to model long-term effects of fast voltage-activated ion channels.
4 LIF-R + Afterspike Currents (LIF-R-ASC)
LIF with additional Reset Rules and Afterspike Currents.
5 LIF-R-ASC + Threshold Adaptation (LIF-R-ASC-A)
All of the above, with an additional voltage-dependent component of threshold.
Please see See the perisomatic biophysical and GLIF technical white papers whitepapers for more details on how these models were created (TODO).
A cell's electrophysiology page displays all available models. Choose a model to see its simulated response to all stimuli presented to the cell. If the required sweeps are available, two model evaluation metrics are computed per model: